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Rhona Stein Selected Research

Neoplasms (Cancer)

6/2018The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target.
8/2011Preclinical studies on targeted delivery of multiple IFNα2b to HLA-DR in diverse hematologic cancers.
10/2010A bispecific antibody-IFNalpha2b immunocytokine targeting CD20 and HLA-DR is highly toxic to human lymphoma and multiple myeloma cells.
6/2010Therapy of B-cell malignancies by anti-HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways.
10/2009CD20-targeted tetrameric interferon-alpha, a novel and potent immunocytokine for the therapy of B-cell lymphomas.
6/2009Hexavalent bispecific antibodies represent a new class of anticancer therapeutics: 1. Properties of anti-CD20/CD22 antibodies in lymphoma.
1/2009Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody.
10/2008Novel designs of multivalent anti-CD20 humanized antibodies as improved lymphoma therapeutics.
9/2007A divalent hapten-peptide induces apoptosis in human non hodgkin lymphoma cell lines targeted by anti-CD20xanti-hapten bispecific antibodies.
9/2007CD74: a new candidate target for the immunotherapy of B-cell neoplasms.
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Rhona Stein Research Topics

Disease

20Neoplasms (Cancer)
06/2018 - 01/2002
12Lymphoma (Lymphomas)
02/2011 - 12/2003
7Multiple Myeloma
10/2010 - 10/2004
7Non-Hodgkin Lymphoma (Lymphosarcoma)
06/2010 - 04/2004
2B-Cell Lymphoma (Lymphoma, B Cell)
10/2009 - 12/2003
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2013
1Hematologic Neoplasms (Hematological Malignancy)
10/2010
1Hairy Cell Leukemia
06/2010
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2010
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
06/2010
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2010
1Leukemia
06/2010
1Burkitt Lymphoma (Burkitt's Lymphoma)
02/2007
1Autoimmune Diseases (Autoimmune Disease)
02/2007
1Residual Neoplasm
04/2005
1Colonic Neoplasms (Colon Cancer)
04/2005
1medullary Thyroid cancer
12/2004
1Neoplasm Metastasis (Metastasis)
12/2004
1Breast Neoplasms (Breast Cancer)
03/2004
1Thyroid Neoplasms (Thyroid Cancer)
01/2002

Drug/Important Bio-Agent (IBA)

15Monoclonal AntibodiesIBA
02/2011 - 01/2002
6HLA-DR Antigens (HLA-DR)IBA
08/2011 - 07/2005
5Rituximab (Mabthera)FDA Link
06/2010 - 04/2004
5AntigensIBA
09/2007 - 01/2002
4milatuzumabIBA
01/2013 - 12/2004
4veltuzumabIBA
10/2009 - 04/2004
3Doxorubicin (Adriamycin)FDA LinkGeneric
04/2009 - 07/2005
3Radioisotopes (Radionuclides)IBA
09/2007 - 10/2004
2Immunoconjugates (Immunoconjugate)IBA
06/2018 - 07/2005
2Immunoglobulin G (IgG)IBA
02/2011 - 06/2010
2AntibodiesIBA
10/2010 - 06/2009
2Bispecific AntibodiesIBA
06/2009 - 09/2007
2Complement System Proteins (Complement)IBA
01/2009 - 04/2004
2epratuzumabIBA
02/2007 - 04/2004
2IodineIBA
04/2005 - 03/2004
2Dacarbazine (DIC)FDA LinkGeneric
12/2004 - 01/2002
2chloramine-T (Clorina)IBA
03/2004 - 01/2003
1Glycoproteins (Glycoprotein)IBA
06/2018
1Irinotecan (Camptosar)FDA LinkGeneric
06/2018
1Surface Antigens (Surface Antigen)IBA
06/2018
1sacituzumab govitecanIBA
06/2018
1HLA Antigens (Human Leukocyte Antigens)IBA
02/2011
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
06/2010
1IMMU-114IBA
06/2010
1JNK Mitogen-Activated Protein KinasesIBA
06/2010
1Interferon-alpha (Interferon Alfa)IBA
10/2009
1Interferon-alpha2bIBA
10/2009
1Interferon alpha-2 (Roferon-A)FDA Link
10/2009
1LipidsIBA
06/2009
1Bortezomib (Velcade)FDA Link
04/2009
1Dexamethasone (Maxidex)FDA LinkGeneric
04/2009
1Humanized Monoclonal AntibodiesIBA
10/2008
1HaptensIBA
09/2007
1IsotopesIBA
09/2007
1Peptides (Polypeptides)IBA
09/2007
1Ribonucleases (Ribonuclease)IBA
09/2007
1IMMU-110IBA
07/2005
1Carcinoembryonic AntigenIBA
12/2004
1labetuzumabIBA
12/2004
1Messenger RNA (mRNA)IBA
10/2004
1ThymidineIBA
10/2004
1Proteins (Proteins, Gene)FDA Link
10/2004
1AnthracyclinesIBA
12/2003
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2002
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
04/2002
1Celecoxib (Celebrex)FDA Link
04/2002
1rofecoxib (Vioxx)FDA Link
04/2002

Therapy/Procedure

13Therapeutics
02/2011 - 04/2002
3Immunotherapy
06/2018 - 09/2007
3Radioimmunotherapy
04/2005 - 01/2002
2Drug Therapy (Chemotherapy)
12/2004 - 01/2002
1Combined Modality Therapy
01/2002